Results of cranial electrotherapy stimulation to children with mixed anxiety and depressive disorder
2007
By Chen Yixin, Yu Lin, Zhang Jiuping, Li Lejia, Chen Tunong, and Chen Yi.

Abstract
Objective： To analyze the effectiveness of cranial electrotherapy stimulation (CES)
on children with mixed anxiety and depressive disorder (MAD).
Methods: There are two groups
participating in the research, each of which included 30 subjects at the age of 8 to 16 who met MAD
criteria of ICD-10 and whose SDS and SAS scores were more than 40. The experimental group was
treated with CES, and the control group was treated with pseudo-CES．Comparison of SDS, SAS
and α wave of occipital lobe between before and after the treatment was taken between the two
groups.
Results: On SDS, there are 49.60±7.03 in the experimental group and 47.23±5.86 in the
control group before the treatment, but there are 34.08±7.79 in the experimental group and
46.83±10.35 in the control group on SDS after the treatment. On SAS, there are 48.27±7.01 in the
experimental group and 46.03±6.24 in the control group before the treatment, but there are
29.67±6.03 in the experimental group and 39.17±12.73 in the control group on SDS after the
treatment. ANOVA indicated that the treatment was significantly effective. The α1 and α2 of
occipital lobe improved more in the experimental group.
Conclusion: CES is effective for treating children with MAD. CES can affect brain electrical activity mapping of occipital lobe.

Subjects and Methods-Methods, Statistical Analysis
Results-Efficacy, Changes in EEG of Occipital Lobes of the Experimental Group and the Control Group, Discussion.
Shanghai-Archives-of-Psychiatry-2007-English

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