A Comparative Study of Anxiety Disorders Treatment with Paroxetine Associated with Cranial Electrotherapy Stimulation Therapy

Medical Innovation of China

2014

By LU Ling, HU Jun.

 

Abstract
Objective: To explore the add-on effect of cranial electrotherapy stimulation therapy in the treatment of anxiety disorders.
Method: One hundred and twenty patients with anxiety disorder were randomly divided into the study group and the CES control group, each group having 60 cases. All of them were given treatment of paroxetine (Paxil) for 6 weeks. In addition, patients in the study group conducted cranial electrotherapy stimulation therapy daily in 6 weeks (42 times). The efficacy was assessed with the Hamilton anxiety scale (HAM-A) and clinical global impression scale (CGI-SI), quality of life was assessed with the World Health Oorganization quality of life questionnaire (WHOQOL-BREF) before and after treatment.
Result: After 6 weeks of treatment the significant efficacy rates of the study group and the control group were 76.67% and 53.33% respectively, and the differences between the two groups were statistically significant (P<0.05). The scores of HAM-A and CGI-SI in both groups after treatment were significantly decreased from before treatment scores (P<0.05). However, the scores of HAM-A (P<0.01) and CGI-SI (P<0.05) in the CES group was reduced more significantly than the control group at the 6th weekend after treatment. The score in four areas of quality of life measures were significantly improved after treatment in the two groups (P<0.05). The physiological domain score in the CES study group was increased significantly over the use of paroxetine alone (P<0.05).
Conclusion: Treating anxiety disorders with paroxetine associated with cranial electrotherapy stimulation therapy is better than with paroxetine by itself
Materials and Methods- General Information, Methods , Statistical processing
Results
Discussion

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